CD8 clinical question

mann0002@mc.duke.edu
Wed, 28 Feb 1996 10:22 -0500 (EST)

I have been asked what is the significance of a decreased CD8 count.
The patient in question is a 35 year old woman with a mildly
increased CD4/CD8 ratio with a CD4 count of 460 and a CD8 count of
58. She is HIV negative and has a poorly characterized autoimmune
disease which is reportedly not SLE.
What is the significance of this decrease in CD8?
Thanks for any help you can give me.

Karen Mann
Clinical Flow Cytometry
Duke Univ Medical Center