Re: Clinical Question

Jan Nelson (j.nelson@auckland.ac.nz)
Thu, 29 Feb 1996 10:33:20 NZS

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The phenotype sounds typical of T- LGL LPD which has variable expression
of CD56,57 and 16. Have you checked the morphology of the cells to see
if they are large granular lymphocytes? We usually follow up with gene
rearrangement anaylsis for TCR beta and gamma to confirm clonality.

There are a number of good reviews on LPD which include these disorders:
Blood 1993, 82: 1-14
Blood Reviews, 1995, 9: 234-250
"The Lymphid Leukaemias"1990, Ed.Catovsky and Foa
Jan Nelson
Jan Nelson
Department of Molecular Medicine
Auckland University School of Medicine
Private Bag, Auckland NZ
Phone: (+64)(9)373-7599 ext 6381
Fax: (+64)(9)373-7492
E-mail: j.nelson@auckland.ac.nz

Next message: James Weaver 301-594-5879 FAX 301-594-3037: "Mab vs human Zeta-globin??"
Previous message: Dr. Huw S.: "Re: old HP hard drive"
Maybe in reply to: Maryalice Stetler-Stevenson: "Clinical Question"