Re: Re : Clinical Question

Walter Sharp (102675.320@compuserve.com)
29 Feb 96 00:46:24 EST

As you say it could very well be a malignant clone but I would like to put a
caveat to you.
Our work with malignancies has shown up this same population of "activated"
cytotoxic T cells in almost all our cases, be they Leukaemias, lymphomas or
,indeed, MDS.
I suppose it is their job after all !

The sheer numbers in your peripheral sample are worrying though, as is the dim
2,5 and 7.
Must go back and look at "our" activated T's in malignancy.

Since this is going back via the list I shall also ask a general clinical
question.

Has anyone noticed dual CD4/CD8 thymocytes in the peripheral circulation of B
cell lymphoma patients as we occasionally have ?
Has anyone an explanation/hypothesis ?

Wal Sharp
SQU
Sultanate of Oman