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> One of our investigators ask me question about percent CD45RO+ cells
> in mouse PBL. I couldn't think off the top, the percent. Could someone
> help me on this before I have to go hit the literature.
CD45RO+ cells in mice serve mostly as memory cells. The numbers of memory
cells increase with advancing age,depending on animal history (mostly
conventional vs. specific pathogen - free housing. I do not have figures for
PBL at hand, but for the murine spleen T cells it varies from around 20% in
the young (3 mo) to more than 60% in old SPF mice (say 2 years old).
Hope this helps -
Jacek
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Jacek M. Witkowski MD, Ph.D
Department of Histology and Immunology
Medical University of Gdansk, Poland
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