D Values for Dr. Kilidare
Kenneth Ault (70541.1431@CompuServe.COM)
24 Jun 94 13:31:46 EDT
In reply to the request for information about the use of D values:
I know nothing about the practice at the Mayo Clinic, but as one who was
involved with originally perpetrating the use of the K-S test in analyzing kappa
and lambda labeling of B cells I am happy to testify that the D value expressed
as a percent (i.e. multiplied by 100) is the figure that is usually used. Used
in this way it is best thought of not as a test statistic but as a rough measure
of the magnitude of the difference between the two curves.
If one does "mixing" experiments it turns out that the D value is roughly
proportional to the number of abnormal (clonal) B cells added to the mixture and
thus it can be thought of as an estimate of the proportion of abnormal cells
among those that were analyzed.
I hope that this is helpful.
CD-ROM Vol 3 was produced by Monica M. Shively and other staff at the
Purdue University Cytometry Laboratories and distributed free of charge
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If you have any comments please direct them to
Dr. J. Paul Robinson, Professor & Director,
PUCL, Purdue University, West Lafayette, IN 47907.
Phone: (765)-494-0757;
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