Re: CD10 expression in follicular lymphoma
Anna Porwit (anpo@mb.ks.se)
Tue, 7 Jan 1997 10:46:44 +0100
>
>Happy year year to one and all.
>
>I have a bone marrow biopsy on a 63 yr old male with severe peripheral
>pancytopenea. Biopsy is atypical lymphoid infiltrate consistent with NHL
>small cleaved cell. Light scatter shows a single population of small
>lymphocytes. The phenotype is CD5-, CD19+, CD22+, CD10-, CD20+, CD25-,
>CD23-, CD103-, CD11c-, kappa bright positive, lambda negative. Seems to fit
>best with follicular lymphoma except for the CD10 negativity. I wonder what
>others of you may think about this phenotype?
>
>Thanks,
>
>Brent Dorsett
>Director, Special Pathology Laboratories, Lenox Hill Hospital, NYC
>
>Hi!
The immunophenotype may be consistent with immunocytoma alt. marginal cell
lymphoma according to REAL classification. Most of the FCC NHL should be CD10+!.
Happy New New Year to everybody!
Anna Porwit MD, PHD
Haematopathology, Karolinska Hospital, Sweden
>
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