I believe that the only available antibody that recognizes activated
GPIIb/IIIa is the PAC-1 IgM antibody and it is sold by Becton-Dickinson.
They sell it for $345 for 200ug of unlabelled antibody and $225 for the
FITC conjugate. There is no IgG equivalent antibody available either
commercially or that has been described in the literature.
Bradley
>I am looking for a commercial source of the platelet activation dependant
>antibody PAC-1.
>
>I have found a PAC-1, but it is an IgM and I would prefer IgG1 if it is
>available.
>
>I hope somebody can help me.
>
>Thanks
>Dorte Christiansen
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Bradley Bone
Immunology Core Facility Coordinator
Mayo Clinic Scottsdale
Johnson Research Building
13400 E. Shea Blvd.
Scottsdale, AZ 85259
Phone: (602)301-7131
Pager: (602)301-5753
FAX: (602)301-7017
E-mail: bone.bradley@mayo.edu