Re: Clinical Question

STEVEN DAVID GORE (sdgore@welchlink.welch.jhu.edu)
Wed, 28 Feb 1996 09:16:02 -0500 (EST)

On Mon, 26 Feb 1996, Maryalice Stetler-Stevenson wrote:

>
> Flow: 75% lymphocytes with 97% T-cells. Approximately 70% of the
> lymphocytes are CD3+ T-cells with abnormally dim CD2, CD5 and CD7
> expression; bright CD8; negative for CD56 and CD16 as well as + for CD38
> and HLADR. They are alpha beta T-cells.
> I think this is highly abnormal and I bet malignant. Any comments?
>

Why not T-CLL? I'd see if TCR-beta showed a clonal rearrangement.

Steve GOre
Johns Hopkins Oncology Center