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1) Lymphocyte development localization
2) Intervenants of the immune response to bacterial infection
3) Intervenants of the immune response to viral infection
We would like to make these ideas apparent from the study of cytometric
data.
About point 1) Do you think it would be possible to compare B and T cell
populations between control mice, thymectomized or nude mice and irradiated
mice?
About point 2) Do you think it would be possible to detect any
quantitative variation in some CD4 or B cell populations during a bacterial
infection? We want to show that the infection has actually induced a clonal
expansion of these populations and that the cells of these populations
exhibit interleukin receptors on their plasmic membranes. Is there any
marker of plasmocyte differenciation?
About point 3) Do you think it would be possible to detect any quantitative
variation in some CD4 and CD8 populations during a viral infection? We want
to show that the infection has induced a clonal expansion of certain CD4
and CD8 populations that exhibit expression of interleukin receptors? Is
there any cytotoxic T cell specific marker?
We would also like to know whether any intervention of MHC can be shown in
the immune response to viral infection?
Thanks again for your collaboration.
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CD-ROM Vol 3 was produced by Monica M. Shively and other staff at the
Purdue University Cytometry Laboratories and distributed free of charge
as an educational service to the cytometry community.
If you have any comments please direct them to
Dr. J. Paul Robinson, Professor & Director,
PUCL, Purdue University, West Lafayette, IN 47907.
Phone: (765)-494-0757;
FAX(765) 494-0517;
Web